A study in the August 25 New England Journal of Medicine examined the use of the drug Misoprostol (normally used for stomach conditions) compared to vacuum aspiration for early miscarriage. 652 women with 1st trimester miscarriage were assigned to either the drug (491 women) or the surgical procedure (161 women), and followed for whether expulsion was complete at a certain number of days after treatment. 84% of women were sucessfully treated with the drug, and 97% were successfully treated with aspiration. Women receiving the drug were more likely to experience reduced hemoglobin, nausea, vomiting, and diarrhea. However, 83% of women receiving Misoprostol would recommend the drug (compared to 83% for aspiration) and 78% would use the treatment again (compared to 75% for aspiration).
A summary is available from NIH News, and the abstract is available from NEJM.
Technorati Tags: miscarriage; New England Journal of Medicine; research
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